Karen Adelman, PhD
Professor of Biological Chemistry and Molecular Pharmacology, Harvard Medical School
Transcription start site profiling uncovers divergent transcription and enhancer-associated RNAs in Drosophila melanogaster.
Authors: Authors: Meers MP, Adelman K, Duronio RJ, Strahl BD, McKay DJ, Matera AG.
BMC Genomics
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BMC Genomics
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SnapShot: Transcription regulation: pausing.
Using ChIP-chip and ChIP-seq to study the regulation of gene expression: genome-wide localization studies reveal widespread regulation of transcription elongation.
Widespread transcriptional pausing and elongation control at enhancers.
Authors: Authors: Henriques T, Scruggs BS, Inouye MO, Muse GW, Williams LH, Burkholder AB, Lavender CA, Fargo DC, Adelman K.
Genes Dev
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Genes Dev
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Catching the waves: following the leading edge of elongating RNA polymerase II.
NELF-mediated stalling of Pol II can enhance gene expression by blocking promoter-proximal nucleosome assembly.
Authors: Authors: Gilchrist DA, Nechaev S, Lee C, Ghosh SK, Collins JB, Li L, Gilmour DS, Adelman K.
Genes Dev
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Genes Dev
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The kinetics of pre-mRNA splicing in the Drosophila genome and the influence of gene architecture.
Authors: Authors: Pai AA, Henriques T, McCue K, Burkholder A, Adelman K, Burge CB.
Elife
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Elife
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Defining the status of RNA polymerase at promoters.
Authors: Authors: Core LJ, Waterfall JJ, Gilchrist DA, Fargo DC, Kwak H, Adelman K, Lis JT.
Cell Rep
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Cell Rep
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Promoter-proximal Pol II: when stalling speeds things up.
Enhanced chromatin accessibility of the dosage compensated Drosophila male X-chromosome requires the CLAMP zinc finger protein.
Authors: Authors: Urban J, Kuzu G, Bowman S, Scruggs B, Henriques T, Kingston R, Adelman K, Tolstorukov M, Larschan E.
PLoS One
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PLoS One
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