Karen Adelman, PhD
Professor of Biological Chemistry and Molecular Pharmacology, Harvard Medical School
Moonshine illuminates a developmental role for regulated transcription elongation.
Interaction of T4 AsiA with its target sites in the RNA polymerase sigma70 subunit leads to distinct and opposite effects on transcription.
Authors: Authors: Minakhin L, Niedziela-Majka A, Kuznedelov K, Adelman K, Urbauer JL, Heyduk T, Severinov K.
J Mol Biol
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J Mol Biol
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Promoter-proximal pausing of RNA polymerase II: a nexus of gene regulation.
The Importance of Controlling Transcription Elongation at Coding and Noncoding RNA Loci.
Authors: Authors: Scruggs BS, Adelman K.
Cold Spring Harb Symp Quant Biol
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Cold Spring Harb Symp Quant Biol
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Taking MLL through the MudPIT: identification of novel complexes that bring together MLL-fusion proteins and transcription elongation factors.
Single molecule analysis of RNA polymerase elongation reveals uniform kinetic behavior.
Authors: Authors: Adelman K, La Porta A, Santangelo TJ, Lis JT, Roberts JW, Wang MD.
Proc Natl Acad Sci U S A
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Proc Natl Acad Sci U S A
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Negative elongation factor is essential for endometrial function.
Authors: Authors: Hewitt SC, Li R, Adams N, Winuthayanon W, Hamilton KJ, Donoghue LJ, Lierz SL, Garcia M, Lydon JP, DeMayo FJ, Adelman K, Korach KS.
FASEB J
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FASEB J
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Preparing the first responders: building the inflammatory transcriptome from the ground up.
RNA polymerase II stalling mediates cytokine gene expression.
How does Pol II overcome the nucleosome barrier?