Karen Adelman, PhD

Professor of Biological Chemistry and Molecular Pharmacology, Harvard Medical School
Using ChIP-chip and ChIP-seq to study the regulation of gene expression: genome-wide localization studies reveal widespread regulation of transcription elongation.
Authors: Authors: Gilchrist DA, Fargo DC, Adelman K.
Methods
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Widespread transcriptional pausing and elongation control at enhancers.
Authors: Authors: Henriques T, Scruggs BS, Inouye MO, Muse GW, Williams LH, Burkholder AB, Lavender CA, Fargo DC, Adelman K.
Genes Dev
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Catching the waves: following the leading edge of elongating RNA polymerase II.
Authors: Authors: Henriques T, Adelman K.
Mol Cell
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NELF-mediated stalling of Pol II can enhance gene expression by blocking promoter-proximal nucleosome assembly.
Authors: Authors: Gilchrist DA, Nechaev S, Lee C, Ghosh SK, Collins JB, Li L, Gilmour DS, Adelman K.
Genes Dev
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The kinetics of pre-mRNA splicing in the Drosophila genome and the influence of gene architecture.
Authors: Authors: Pai AA, Henriques T, McCue K, Burkholder A, Adelman K, Burge CB.
Elife
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Defining the status of RNA polymerase at promoters.
Authors: Authors: Core LJ, Waterfall JJ, Gilchrist DA, Fargo DC, Kwak H, Adelman K, Lis JT.
Cell Rep
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Promoter-proximal Pol II: when stalling speeds things up.
Authors: Authors: Nechaev S, Adelman K.
Cell Cycle
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Enhanced chromatin accessibility of the dosage compensated Drosophila male X-chromosome requires the CLAMP zinc finger protein.
Authors: Authors: Urban J, Kuzu G, Bowman S, Scruggs B, Henriques T, Kingston R, Adelman K, Tolstorukov M, Larschan E.
PLoS One
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Promoter-proximal pausing of RNA polymerase II: emerging roles in metazoans.
Authors: Authors: Adelman K, Lis JT.
Nat Rev Genet
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RNA polymerase stalling at developmental control genes in the Drosophila melanogaster embryo.
Authors: Authors: Zeitlinger J, Stark A, Kellis M, Hong JW, Nechaev S, Adelman K, Levine M, Young RA.
Nat Genet
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