Karen Adelman, PhD

Professor of Biological Chemistry and Molecular Pharmacology, Harvard Medical School
Numerous recursive sites contribute to accuracy of splicing in long introns in flies.
Authors: Authors: Pai AA, Paggi JM, Yan P, Adelman K, Burge CB.
PLoS Genet
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Acetylation of RNA polymerase II regulates growth-factor-induced gene transcription in mammalian cells.
Authors: Authors: Schröder S, Herker E, Itzen F, He D, Thomas S, Gilchrist DA, Kaehlcke K, Cho S, Pollard KS, Capra JA, Schnölzer M, Cole PA, Geyer M, Bruneau BG, Adelman K, Ott M.
Mol Cell
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Global analysis of short RNAs reveals widespread promoter-proximal stalling and arrest of Pol II in Drosophila.
Authors: Authors: Nechaev S, Fargo DC, dos Santos G, Liu L, Gao Y, Adelman K.
Science
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Solution structure and stability of the anti-sigma factor AsiA: implications for novel functions.
Authors: Authors: Urbauer JL, Simeonov MF, Urbauer RJ, Adelman K, Gilmore JM, Brody EN.
Proc Natl Acad Sci U S A
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Transcriptional speed bumps revealed in high resolution.
Authors: Authors: Adelman K, Henriques T.
Nature
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Stable pausing by RNA polymerase II provides an opportunity to target and integrate regulatory signals.
Authors: Authors: Henriques T, Gilchrist DA, Nechaev S, Bern M, Muse GW, Burkholder A, Fargo DC, Adelman K.
Mol Cell
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Immediate mediators of the inflammatory response are poised for gene activation through RNA polymerase II stalling.
Authors: Authors: Adelman K, Kennedy MA, Nechaev S, Gilchrist DA, Muse GW, Chinenov Y, Rogatsky I.
Proc Natl Acad Sci U S A
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Emerging Roles of Non-Coding RNA Transcription.
Authors: Authors: Kaikkonen MU, Adelman K.
Trends Biochem Sci
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Glucocorticoid receptor represses proinflammatory genes at distinct steps of the transcription cycle.
Authors: Authors: Gupte R, Muse GW, Chinenov Y, Adelman K, Rogatsky I.
Proc Natl Acad Sci U S A
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Spt6 enhances the elongation rate of RNA polymerase II in vivo.
Authors: Authors: Ardehali MB, Yao J, Adelman K, Fuda NJ, Petesch SJ, Webb WW, Lis JT.
EMBO J
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