Karen Adelman, PhD

Professor of Biological Chemistry and Molecular Pharmacology, Harvard Medical School
Intragenic Enhancers Attenuate Host Gene Expression.
Authors: Authors: Cinghu S, Yang P, Kosak JP, Conway AE, Kumar D, Oldfield AJ, Adelman K, Jothi R.
Mol Cell
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Regulating the regulators: the pervasive effects of Pol II pausing on stimulus-responsive gene networks.
Authors: Authors: Gilchrist DA, Fromm G, dos Santos G, Pham LN, McDaniel IE, Burkholder A, Fargo DC, Adelman K.
Genes Dev
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RNA polymerase is poised for activation across the genome.
Authors: Authors: Muse GW, Gilchrist DA, Nechaev S, Shah R, Parker JS, Grissom SF, Zeitlinger J, Adelman K.
Nat Genet
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ORIO (Online Resource for Integrative Omics): a web-based platform for rapid integration of next generation sequencing data.
Authors: Authors: Lavender CA, Shapiro AJ, Burkholder AB, Bennett BD, Adelman K, Fargo DC.
Nucleic Acids Res
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Coupling polymerase pausing and chromatin landscapes for precise regulation of transcription.
Authors: Authors: Gilchrist DA, Adelman K.
Biochim Biophys Acta
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Drosophila Paf1 modulates chromatin structure at actively transcribed genes.
Authors: Authors: Adelman K, Wei W, Ardehali MB, Werner J, Zhu B, Reinberg D, Lis JT.
Mol Cell Biol
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Mll3 and Mll4 Facilitate Enhancer RNA Synthesis and Transcription from Promoters Independently of H3K4 Monomethylation.
Authors: Authors: Dorighi KM, Swigut T, Henriques T, Bhanu NV, Scruggs BS, Nady N, Still CD, Garcia BA, Adelman K, Wysocka J.
Mol Cell
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Rapid activity-induced transcription of Arc and other IEGs relies on poised RNA polymerase II.
Authors: Authors: Saha RN, Wissink EM, Bailey ER, Zhao M, Fargo DC, Hwang JY, Daigle KR, Fenn JD, Adelman K, Dudek SM.
Nat Neurosci
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Efficient release from promoter-proximal stall sites requires transcript cleavage factor TFIIS.
Authors: Authors: Adelman K, Marr MT, Werner J, Saunders A, Ni Z, Andrulis ED, Lis JT.
Mol Cell
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Histone gene replacement reveals a post-transcriptional role for H3K36 in maintaining metazoan transcriptome fidelity.
Authors: Authors: Meers MP, Henriques T, Lavender CA, McKay DJ, Strahl BD, Duronio RJ, Adelman K, Matera AG.
Elife
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