Karen Adelman, PhD

Professor of Biological Chemistry and Molecular Pharmacology, Harvard Medical School
CDK12 is a transcription elongation-associated CTD kinase, the metazoan ortholog of yeast Ctk1.
Authors: Authors: Bartkowiak B, Liu P, Phatnani HP, Fuda NJ, Cooper JJ, Price DH, Adelman K, Lis JT, Greenleaf AL.
Genes Dev
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Characterization of the interactions between the bacteriophage T4 AsiA protein and RNA polymerase.
Authors: Authors: Simeonov MF, Bieber Urbauer RJ, Gilmore JM, Adelman K, Brody EN, Niedziela-Majka A, Minakhin L, Heyduk T, Urbauer JL.
Biochemistry
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PCIF1 Catalyzes m6Am mRNA Methylation to Regulate Gene Expression.
Authors: Authors: Sendinc E, Valle-Garcia D, Dhall A, Chen H, Henriques T, Navarrete-Perea J, Sheng W, Gygi SP, Adelman K, Shi Y.
Mol Cell
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Pausing of RNA polymerase II regulates mammalian developmental potential through control of signaling networks.
Authors: Authors: Williams LH, Fromm G, Gokey NG, Henriques T, Muse GW, Burkholder A, Fargo DC, Hu G, Adelman K.
Mol Cell
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Moonshine illuminates a developmental role for regulated transcription elongation.
Authors: Authors: Gilchrist DA, Adelman K.
Dev Cell
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Interaction of T4 AsiA with its target sites in the RNA polymerase sigma70 subunit leads to distinct and opposite effects on transcription.
Authors: Authors: Minakhin L, Niedziela-Majka A, Kuznedelov K, Adelman K, Urbauer JL, Heyduk T, Severinov K.
J Mol Biol
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Promoter-proximal pausing of RNA polymerase II: a nexus of gene regulation.
Authors: Authors: Core L, Adelman K.
Genes Dev
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The Importance of Controlling Transcription Elongation at Coding and Noncoding RNA Loci.
Authors: Authors: Scruggs BS, Adelman K.
Cold Spring Harb Symp Quant Biol
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Taking MLL through the MudPIT: identification of novel complexes that bring together MLL-fusion proteins and transcription elongation factors.
Authors: Authors: Fromm G, Adelman K.
Mol Cell
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Single molecule analysis of RNA polymerase elongation reveals uniform kinetic behavior.
Authors: Authors: Adelman K, La Porta A, Santangelo TJ, Lis JT, Roberts JW, Wang MD.
Proc Natl Acad Sci U S A
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