Karen Adelman, PhD

Professor of Biological Chemistry and Molecular Pharmacology, Harvard Medical School
Coupling polymerase pausing and chromatin landscapes for precise regulation of transcription.
Authors: Authors: Gilchrist DA, Adelman K.
Biochim Biophys Acta
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Drosophila Paf1 modulates chromatin structure at actively transcribed genes.
Authors: Authors: Adelman K, Wei W, Ardehali MB, Werner J, Zhu B, Reinberg D, Lis JT.
Mol Cell Biol
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Mll3 and Mll4 Facilitate Enhancer RNA Synthesis and Transcription from Promoters Independently of H3K4 Monomethylation.
Authors: Authors: Dorighi KM, Swigut T, Henriques T, Bhanu NV, Scruggs BS, Nady N, Still CD, Garcia BA, Adelman K, Wysocka J.
Mol Cell
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Rapid activity-induced transcription of Arc and other IEGs relies on poised RNA polymerase II.
Authors: Authors: Saha RN, Wissink EM, Bailey ER, Zhao M, Fargo DC, Hwang JY, Daigle KR, Fenn JD, Adelman K, Dudek SM.
Nat Neurosci
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Efficient release from promoter-proximal stall sites requires transcript cleavage factor TFIIS.
Authors: Authors: Adelman K, Marr MT, Werner J, Saunders A, Ni Z, Andrulis ED, Lis JT.
Mol Cell
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Histone gene replacement reveals a post-transcriptional role for H3K36 in maintaining metazoan transcriptome fidelity.
Authors: Authors: Meers MP, Henriques T, Lavender CA, McKay DJ, Strahl BD, Duronio RJ, Adelman K, Matera AG.
Elife
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Pol II waiting in the starting gates: Regulating the transition from transcription initiation into productive elongation.
Authors: Authors: Nechaev S, Adelman K.
Biochim Biophys Acta
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Molecular mechanism of transcription inhibition by peptide antibiotic Microcin J25.
Authors: Authors: Adelman K, Yuzenkova J, La Porta A, Zenkin N, Lee J, Lis JT, Borukhov S, Wang MD, Severinov K.
Mol Cell
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The Histone Deacetylase SIRT6 Restrains Transcription Elongation via Promoter-Proximal Pausing.
Authors: Authors: Etchegaray JP, Zhong L, Li C, Henriques T, Ablondi E, Nakadai T, Van Rechem C, Ferrer C, Ross KN, Choi JE, Samarakkody A, Ji F, Chang A, Sadreyev RI, Ramaswamy S, Nechaev S, Whetstine JR, Roeder RG, Adelman K, Goren A, Mostoslavsky R.
Mol Cell
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Non-coding RNA: More uses for genomic junk.
Authors: Authors: Adelman K, Egan E.
Nature
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