Luk Vandenberghe, PhD

Associate Professor of Ophthalmology, Massachusetts Eye and Ear Infirmary
AAV Engineering Identifies a Species Barrier That Highlights a Portal to the Brain.
Authors: Authors: Vandenberghe LH.
Mol Ther
View full abstract on Pubmed
Genome editing abrogates angiogenesis in vivo.
Authors: Authors: Huang X, Zhou G, Wu W, Duan Y, Ma G, Song J, Xiao R, Vandenberghe L, Zhang F, D'Amore PA, Lei H.
Nat Commun
View full abstract on Pubmed
Promising and delivering gene therapies for vision loss.
Authors: Authors: Carvalho LS, Vandenberghe LH.
Vision Res
View full abstract on Pubmed
Evaluation of adeno-associated viral vectors for liver-directed gene transfer in dogs.
Authors: Authors: Bell P, Gao G, Haskins ME, Wang L, Sleeper M, Wang H, Calcedo R, Vandenberghe LH, Chen SJ, Weisse C, Withnall E, Wilson JM.
Hum Gene Ther
View full abstract on Pubmed
Host immune responses to chronic adenovirus infections in human and nonhuman primates.
Authors: Authors: Calcedo R, Vandenberghe LH, Roy S, Somanathan S, Wang L, Wilson JM.
J Virol
View full abstract on Pubmed
Adeno-associated viruses undergo substantial evolution in primates during natural infections.
Authors: Authors: Gao G, Alvira MR, Somanathan S, Lu Y, Vandenberghe LH, Rux JJ, Calcedo R, Sanmiguel J, Abbas Z, Wilson JM.
Proc Natl Acad Sci U S A
View full abstract on Pubmed
Therapeutic AAV Gene Transfer to the Nervous System: A Clinical Reality.
Authors: Authors: Hudry E, Vandenberghe LH.
Neuron
View full abstract on Pubmed
Corrigendum: Cochlear gene therapy with ancestral AAV in adult mice: complete transduction of inner hair cells without cochlear dysfunction.
Authors: Authors: Suzuki J, Hashimoto K, Xiao R, Vandenberghe LH, Liberman MC.
Sci Rep
View full abstract on Pubmed
Formation of newly synthesized adeno-associated virus capsids in the cell nucleus.
Authors: Authors: Bell P, Vandenberghe LH, Wilson JM.
Hum Gene Ther Methods
View full abstract on Pubmed
Efficient and stable transduction of dopaminergic neurons in rat substantia nigra by rAAV 2/1, 2/2, 2/5, 2/6.2, 2/7, 2/8 and 2/9.
Authors: Authors: Van der Perren A, Toelen J, Carlon M, Van den Haute C, Coun F, Heeman B, Reumers V, Vandenberghe LH, Wilson JM, Debyser Z, Baekelandt V.
Gene Ther
View full abstract on Pubmed