Luk Vandenberghe, PhD

Associate Professor of Ophthalmology, Massachusetts Eye and Ear Infirmary
Cross-Packaging and Capsid Mosaic Formation in Multiplexed AAV Libraries.
Authors: Authors: Schmit PF, Pacouret S, Zinn E, Telford E, Nicolaou F, Broucque F, Andres-Mateos E, Xiao R, Penaud-Budloo M, Bouzelha M, Jaulin N, Adjali O, Ayuso E, Vandenberghe LH.
Mol Ther Methods Clin Dev
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An Alternate Route for Adeno-associated Virus (AAV) Entry Independent of AAV Receptor.
Authors: Authors: Dudek AM, Pillay S, Puschnik AS, Nagamine CM, Cheng F, Qiu J, Carette JE, Vandenberghe LH.
J Virol
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What Is Next for Retinal Gene Therapy?
Authors: Authors: Vandenberghe LH.
Cold Spring Harb Perspect Med
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Human CRB1-associated retinal degeneration: comparison with the rd8 Crb1-mutant mouse model.
Authors: Authors: Aleman TS, Cideciyan AV, Aguirre GK, Huang WC, Mullins CL, Roman AJ, Sumaroka A, Olivares MB, Tsai FF, Schwartz SB, Vandenberghe LH, Limberis MP, Stone EM, Bell P, Wilson JM, Jacobson SG.
Invest Ophthalmol Vis Sci
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Isolation and characterization of adenoviruses persistently shed from the gastrointestinal tract of non-human primates.
Authors: Authors: Roy S, Vandenberghe LH, Kryazhimskiy S, Grant R, Calcedo R, Yuan X, Keough M, Sandhu A, Wang Q, Medina-Jaszek CA, Plotkin JB, Wilson JM.
PLoS Pathog
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Complete nucleotide sequences and genome organization of four chimpanzee adenoviruses.
Authors: Authors: Roy S, Gao G, Clawson DS, Vandenberghe LH, Farina SF, Wilson JM.
Virology
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Filling Adeno-Associated Virus Capsids: Estimating Success by Cryo-Electron Microscopy.
Authors: Authors: Subramanian S, Maurer AC, Bator CM, Makhov AM, Conway JF, Turner KB, Marden JH, Vandenberghe LH, Hafenstein SL.
Hum Gene Ther
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Delivery of Adeno-Associated Virus Vectors in Adult Mammalian Inner-Ear Cell Subtypes Without Auditory Dysfunction.
Authors: Authors: Tao Y, Huang M, Shu Y, Ruprecht A, Wang H, Tang Y, Vandenberghe LH, Wang Q, Gao G, Kong WJ, Chen ZY.
Hum Gene Ther
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Perspectives on best practices for gene therapy programs.
Authors: Authors: Cheever TR, Berkley D, Braun S, Brown RH, Byrne BJ, Chamberlain JS, Cwik V, Duan D, Federoff HJ, High KA, Kaspar BK, Klinger KW, Larkindale J, Lincecum J, Mavilio F, McDonald CL, McLaughlin J, Weiss McLeod B, Mendell JR, Nuckolls G, Stedman HH, Tagle DA, Vandenberghe LH, Wang H, Wernett PJ, Wilson JM, Porter JD, Gubitz AK.
Hum Gene Ther
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Dosage thresholds for AAV2 and AAV8 photoreceptor gene therapy in monkey.
Authors: Authors: Vandenberghe LH, Bell P, Maguire AM, Cearley CN, Xiao R, Calcedo R, Wang L, Castle MJ, Maguire AC, Grant R, Wolfe JH, Wilson JM, Bennett J.
Sci Transl Med
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