Luk Vandenberghe, PhD

Associate Professor of Ophthalmology, Massachusetts Eye and Ear Infirmary
Transduction efficiencies of novel AAV vectors in mouse airway epithelium in vivo and human ciliated airway epithelium in vitro.
Authors: Authors: Limberis MP, Vandenberghe LH, Zhang L, Pickles RJ, Wilson JM.
Mol Ther
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DC-SIGN and DC-SIGNR bind ebola glycoproteins and enhance infection of macrophages and endothelial cells.
Authors: Authors: Simmons G, Reeves JD, Grogan CC, Vandenberghe LH, Baribaud F, Whitbeck JC, Burke E, Buchmeier MJ, Soilleux EJ, Riley JL, Doms RW, Bates P, Pöhlmann S.
Virology
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Residues on Adeno-associated Virus Capsid Lumen Dictate Interactions and Compatibility with the Assembly-Activating Protein.
Authors: Authors: Maurer AC, Cepeda Diaz AK, Vandenberghe LH.
J Virol
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AAV-ID: A Rapid and Robust Assay for Batch-to-Batch Consistency Evaluation of AAV Preparations.
Authors: Authors: Pacouret S, Bouzelha M, Shelke R, Andres-Mateos E, Xiao R, Maurer A, Mevel M, Turunen H, Barungi T, Penaud-Budloo M, Broucque F, Blouin V, Moullier P, Ayuso E, Vandenberghe LH.
Mol Ther
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Gene therapy: charting a future course--summary of a National Institutes of Health Workshop, April 12, 2013.
Authors: Authors: O'Reilly M, Federoff HJ, Fong Y, Kohn DB, Patterson AP, Ahmed N, Asokan A, Boye SE, Crystal RG, De Oliveira S, Gargiulo L, Harper SQ, Ikeda Y, Jambou R, Montgomery M, Prograis L, Rosenthal E, Sterman DH, Vandenberghe LH, Zoloth L, Abedi M, Adair J, Adusumilli PS, Goins WF, Gray J, Monahan P, Popplewell L, Sena-Esteves M, Tannous B, Weber T, Wierda W, Gopal-Srivastava R, McDonald CL, Rosenblum D, Corrigan-Curay J.
Hum Gene Ther
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Gene therapy in a humanized mouse model of familial hypercholesterolemia leads to marked regression of atherosclerosis.
Authors: Authors: Kassim SH, Li H, Vandenberghe LH, Hinderer C, Bell P, Marchadier D, Wilson A, Cromley D, Redon V, Yu H, Wilson JM, Rader DJ.
PLoS One
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Tailoring the AAV vector capsid for gene therapy.
Authors: Authors: Vandenberghe LH, Wilson JM, Gao G.
Gene Ther
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Therapeutic AAV Gene Transfer to the Nervous System: A Clinical Reality.
Authors: Authors: Hudry E, Vandenberghe LH.
Neuron
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Cochlear gene therapy with ancestral AAV in adult mice: complete transduction of inner hair cells without cochlear dysfunction.
Authors: Authors: Suzuki J, Hashimoto K, Xiao R, Vandenberghe LH, Liberman MC.
Sci Rep
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The structure of AAVrh32.33, a novel gene delivery vector.
Authors: Authors: Mikals K, Nam HJ, Van Vliet K, Vandenberghe LH, Mays LE, McKenna R, Wilson JM, Agbandje-McKenna M.
J Struct Biol
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