Luk Vandenberghe, PhD

Associate Professor of Ophthalmology, Massachusetts Eye and Ear Infirmary
Adeno-associated virus capsid structure drives CD4-dependent CD8+ T cell response to vector encoded proteins.
Authors: Authors: Mays LE, Vandenberghe LH, Xiao R, Bell P, Nam HJ, Agbandje-McKenna M, Wilson JM.
J Immunol
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Clades of Adeno-associated viruses are widely disseminated in human tissues.
Authors: Authors: Gao G, Vandenberghe LH, Alvira MR, Lu Y, Calcedo R, Zhou X, Wilson JM.
J Virol
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GPR108 Is a Highly Conserved AAV Entry Factor.
Authors: Authors: Dudek AM, Zabaleta N, Zinn E, Pillay S, Zengel J, Porter C, Franceschini JS, Estelien R, Carette JE, Zhou GL, Vandenberghe LH.
Mol Ther
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Evaluating Efficiencies of Dual AAV Approaches for Retinal Targeting.
Authors: Authors: Carvalho LS, Turunen HT, Wassmer SJ, Luna-Velez MV, Xiao R, Bennett J, Vandenberghe LH.
Front Neurosci
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Efficient transduction and optogenetic stimulation of retinal bipolar cells by a synthetic adeno-associated virus capsid and promoter.
Authors: Authors: Cronin T, Vandenberghe LH, Hantz P, Juttner J, Reimann A, Kacsó AE, Huckfeldt RM, Busskamp V, Kohler H, Lagali PS, Roska B, Bennett J.
EMBO Mol Med
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Identification and functional characterization in vivo of a novel splice variant of LDLR in rhesus macaques.
Authors: Authors: Kassim SH, Vandenberghe LH, Hovhannisyan R, Wilson JM, Rader DJ.
Physiol Genomics
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Functional cystic fibrosis transmembrane conductance regulator expression in cystic fibrosis airway epithelial cells by AAV6.2-mediated segmental trans-splicing.
Authors: Authors: Song Y, Lou HH, Boyer JL, Limberis MP, Vandenberghe LH, Hackett NR, Leopold PL, Wilson JM, Crystal RG.
Hum Gene Ther
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Folate receptor alpha and caveolae are not required for Ebola virus glycoprotein-mediated viral infection.
Authors: Authors: Simmons G, Rennekamp AJ, Chai N, Vandenberghe LH, Riley JL, Bates P.
J Virol
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In Situ Modification of Tissue Stem and Progenitor Cell Genomes.
Authors: Authors: Goldstein JM, Tabebordbar M, Zhu K, Wang LD, Messemer KA, Peacker B, Ashrafi Kakhki S, Gonzalez-Celeiro M, Shwartz Y, Cheng JKW, Xiao R, Barungi T, Albright C, Hsu YC, Vandenberghe LH, Wagers AJ.
Cell Rep
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Single stranded adeno-associated virus achieves efficient gene transfer to anterior segment in the mouse eye.
Authors: Authors: Wang L, Xiao R, Andres-Mateos E, Vandenberghe LH.
PLoS One
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