Marc Kirschner, PhD

John Franklin Enders University Professor of Systems Biology, Harvard Medical School
SCIENTIFIC COMMUNITY. Preprints for the life sciences.
Authors: Authors: Berg JM, Bhalla N, Bourne PE, Chalfie M, Drubin DG, Fraser JS, Greider CW, Hendricks M, Jones C, Kiley R, King S, Kirschner MW, Krumholz HM, Lehmann R, Leptin M, Pulverer B, Rosenzweig B, Spiro JE, Stebbins M, Strasser C, Swaminathan S, Turner P, Vale RD, VijayRaghavan K, Wolberger C.
Science
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Quantitative Lys-?-Gly-Gly (diGly) proteomics coupled with inducible RNAi reveals ubiquitin-mediated proteolysis of DNA damage-inducible transcript 4 (DDIT4) by the E3 ligase HUWE1.
Authors: Authors: Thompson JW, Nagel J, Hoving S, Gerrits B, Bauer A, Thomas JR, Kirschner MW, Schirle M, Luchansky SJ.
J Biol Chem
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Multiple phases of chondrocyte enlargement underlie differences in skeletal proportions.
Authors: Authors: Cooper KL, Oh S, Sung Y, Dasari RR, Kirschner MW, Tabin CJ.
Nature
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ß-catenin specifies the endomesoderm and defines the posterior organizer of the hemichordate Saccoglossus kowalevskii.
Authors: Authors: Darras S, Gerhart J, Terasaki M, Kirschner M, Lowe CJ.
Development
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The incoherent feedforward loop can provide fold-change detection in gene regulation.
Authors: Authors: Goentoro L, Shoval O, Kirschner MW, Alon U.
Mol Cell
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Anaphase initiation is regulated by antagonistic ubiquitination and deubiquitination activities.
Authors: Authors: Stegmeier F, Rape M, Draviam VM, Nalepa G, Sowa ME, Ang XL, McDonald ER, Li MZ, Hannon GJ, Sorger PK, Kirschner MW, Harper JW, Elledge SJ.
Nature
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Domain structure of separase and its binding to securin as determined by EM.
Authors: Authors: Viadiu H, Stemmann O, Kirschner MW, Walz T.
Nat Struct Mol Biol
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WAVE2 deficiency reveals distinct roles in embryogenesis and Rac-mediated actin-based motility.
Authors: Authors: Yan C, Martinez-Quiles N, Eden S, Shibata T, Takeshima F, Shinkura R, Fujiwara Y, Bronson R, Snapper SB, Kirschner MW, Geha R, Rosen FS, Alt FW.
EMBO J
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An approach to increased polyplex gene delivery by peptides selected from a phage display library.
Authors: Authors: Morpurgo M, Kirschner M, Radu A.
J Biochem Biophys Methods
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Transient expression and heat-stress-induced co-aggregation of endogenous and heterologous small heat-stress proteins in tobacco protoplasts.
Authors: Authors: Kirschner M, Winkelhaus S, Thierfelder JM, Nover L.
Plant J
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