Marc Kirschner, PhD

John Franklin Enders University Professor of Systems Biology, Harvard Medical School
Hippo pathway mediates resistance to cytotoxic drugs.
Authors: Authors: Gujral TS, Kirschner MW.
Proc Natl Acad Sci U S A
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Opinion: Addressing systemic problems in the biomedical research enterprise.
Authors: Authors: Alberts B, Kirschner MW, Tilghman S, Varmus H.
Proc Natl Acad Sci U S A
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SCF-mediated Cdh1 degradation defines a negative feedback system that coordinates cell-cycle progression.
Authors: Authors: Fukushima H, Ogura K, Wan L, Lu Y, Li V, Gao D, Liu P, Lau AW, Wu T, Kirschner MW, Inuzuka H, Wei W.
Cell Rep
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Cell cycle adaptations of embryonic stem cells.
Authors: Authors: Ballabeni A, Park IH, Zhao R, Wang W, Lerou PH, Daley GQ, Kirschner MW.
Proc Natl Acad Sci U S A
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Quantitative reconstitution of mitotic CDK1 activation in somatic cell extracts.
Authors: Authors: Deibler RW, Kirschner MW.
Mol Cell
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The relationship between evolutionary and physiological variation in hemoglobin.
Authors: Authors: Milo R, Hou JH, Springer M, Brenner MP, Kirschner MW.
Proc Natl Acad Sci U S A
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A microtubule-binding Rho-GEF controls cell morphology during convergent extension of Xenopus laevis.
Authors: Authors: Kwan KM, Kirschner MW.
Development
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Clustering of Nck by a 12-residue Tir phosphopeptide is sufficient to trigger localized actin assembly.
Authors: Authors: Campellone KG, Rankin S, Pawson T, Kirschner MW, Tipper DJ, Leong JM.
J Cell Biol
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Mechanism of regulation of WAVE1-induced actin nucleation by Rac1 and Nck.
Authors: Authors: Eden S, Rohatgi R, Podtelejnikov AV, Mann M, Kirschner MW.
Nature
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Pin1 acts catalytically to promote a conformational change in Cdc25.
Authors: Authors: Stukenberg PT, Kirschner MW.
Mol Cell
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