Marc Kirschner, PhD
John Franklin Enders University Professor of Systems Biology, Harvard Medical School
Intracellular proteolysis.
Geminin, an inhibitor of DNA replication, is degraded during mitosis.
Small pool expression screening: identification of genes involved in cell cycle control, apoptosis, and early development.
Authors: Authors: Lustig KD, Stukenberg PT, McGarry TJ, King RW, Cryns VL, Mead PE, Zon LI, Yuan J, Kirschner MW.
Methods Enzymol
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Methods Enzymol
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Separate domains of p21 involved in the inhibition of Cdk kinase and PCNA.
The biochemical nature of the cell cycle.
Phosphorylation of microtubule-associated protein tau: identification of the site for Ca2(+)-calmodulin dependent kinase and relationship with tau phosphorylation in Alzheimer tangles.
Authors: Authors: Steiner B, Mandelkow EM, Biernat J, Gustke N, Meyer HE, Schmidt B, Mieskes G, Söling HD, Drechsel D, Kirschner MW, Goedert M, Mandelkow E.
EMBO J
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EMBO J
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The polarity and stability of microtubule capture by the kinetochore.
Direct observation of steady-state microtubule dynamics.
Authors: Authors: Kristofferson D, Mitchison T, Kirschner M.
J Cell Biol
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J Cell Biol
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Microtubule assembly nucleated by isolated centrosomes.
A major developmental transition in early Xenopus embryos: I. characterization and timing of cellular changes at the midblastula stage.