Marc Kirschner, PhD

John Franklin Enders University Professor of Systems Biology, Harvard Medical School
Number and evolutionary conservation of alpha- and beta-tubulin and cytoplasmic beta- and gamma-actin genes using specific cloned cDNA probes.
Authors: Authors: Cleveland DW, Lopata MA, MacDonald RJ, Cowan NJ, Rutter WJ, Kirschner MW.
Cell
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Nucleotide binding and phosphorylation in microtubule assembly in vitro.
Authors: Authors: Penningroth SM, Kirschner MW.
J Mol Biol
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Proteomics of phosphorylation and protein dynamics during fertilization and meiotic exit in the Xenopus egg.
Authors: Authors: Presler M, Van Itallie E, Klein AM, Kunz R, Coughlin ML, Peshkin L, Gygi SP, Wühr M, Kirschner MW.
Proc Natl Acad Sci U S A
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The Nuclear Proteome of a Vertebrate.
Authors: Authors: Wühr M, Güttler T, Peshkin L, McAlister GC, Sonnett M, Ishihara K, Groen AC, Presler M, Erickson BK, Mitchison TJ, Kirschner MW, Gygi SP.
Curr Biol
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Exploiting polypharmacology for drug target deconvolution.
Authors: Authors: Gujral TS, Peshkin L, Kirschner MW.
Proc Natl Acad Sci U S A
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Direct observation of mammalian cell growth and size regulation.
Authors: Authors: Son S, Tzur A, Weng Y, Jorgensen P, Kim J, Kirschner MW, Manalis SR.
Nat Methods
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Self-assembly of filopodia-like structures on supported lipid bilayers.
Authors: Authors: Lee K, Gallop JL, Rambani K, Kirschner MW.
Science
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FLEXIQuant: a novel tool for the absolute quantification of proteins, and the simultaneous identification and quantification of potentially modified peptides.
Authors: Authors: Singh S, Springer M, Steen J, Kirschner MW, Steen H.
J Proteome Res
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The processivity of multiubiquitination by the APC determines the order of substrate degradation.
Authors: Authors: Rape M, Reddy SK, Kirschner MW.
Cell
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Toca-1 mediates Cdc42-dependent actin nucleation by activating the N-WASP-WIP complex.
Authors: Authors: Ho HY, Rohatgi R, Lebensohn AM, Li J, Gygi SP, Kirschner MW.
Cell
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