Marc Kirschner, PhD
John Franklin Enders University Professor of Systems Biology, Harvard Medical School
Graded positional information: interpretation for both fate and guidance.
The anaphase-promoting complex mediates TGF-beta signaling by targeting SnoN for destruction.
The KEN box: an APC recognition signal distinct from the D box targeted by Cdh1.
Mitotic inactivation of a human SWI/SNF chromatin remodeling complex.
Authors: Authors: Sif S, Stukenberg PT, Kirschner MW, Kingston RE.
Genes Dev
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Genes Dev
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Expression cloning in the test tube.
Authors: Authors: King RW, Lustig KD, Stukenberg PT, McGarry TJ, Kirschner MW.
Science
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Science
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Early events in DNA replication require cyclin E and are blocked by p21CIP1.
Authors: Authors: Jackson PK, Chevalier S, Philippe M, Kirschner MW.
J Cell Biol
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J Cell Biol
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Pericentrin, a highly conserved centrosome protein involved in microtubule organization.
Authors: Authors: Doxsey SJ, Stein P, Evans L, Calarco PD, Kirschner M.
Cell
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Cell
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mik1 and wee1 cooperate in the inhibitory tyrosine phosphorylation of cdc2.
Authors: Authors: Lundgren K, Walworth N, Booher R, Dembski M, Kirschner M, Beach D.
Cell
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Cell
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Monoclonal antibodies specific for thiophosphorylated proteins recognize Xenopus MPF.
Phosphorylation changes associated with the early cell cycle in Xenopus eggs.