Marc Kirschner, PhD
John Franklin Enders University Professor of Systems Biology, Harvard Medical School
Cyclin B and E2F-1 expression in prostate carcinoma cells treated with the novel retinoid CD437 are regulated by the ubiquitin-mediated pathway.
Authors: Authors: Farhana L, Dawson M, Rishi AK, Zhang Y, Van Buren E, Trivedi C, Reichert U, Fang G, Kirschner MW, Fontana JA.
Cancer Res
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Cancer Res
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Two tandem verprolin homology domains are necessary for a strong activation of Arp2/3 complex-induced actin polymerization and induction of microspike formation by N-WASP.
Authors: Authors: Yamaguchi H, Miki H, Suetsugu S, Ma L, Kirschner MW, Takenawa T.
Proc Natl Acad Sci U S A
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Proc Natl Acad Sci U S A
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Identification of a new uracil-DNA glycosylase family by expression cloning using synthetic inhibitors.
Authors: Authors: Haushalter KA, Todd Stukenberg MW, Kirschner MW, Verdine GL.
Curr Biol
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Curr Biol
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Sizzled: a secreted Xwnt8 antagonist expressed in the ventral marginal zone of Xenopus embryos.
Authors: Authors: Salic AN, Kroll KL, Evans LM, Kirschner MW.
Development
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Development
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Mutagenic analysis of the destruction signal of mitotic cyclins and structural characterization of ubiquitinated intermediates.
Mitosis in transition.
Microtubule polymer assembly and transport during axonal elongation.
Tau consists of a set of proteins with repeated C-terminal microtubule-binding domains and variable N-terminal domains.
Authors: Authors: Himmler A, Drechsel D, Kirschner MW, Martin DW.
Mol Cell Biol
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Mol Cell Biol
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Microtubule assembly in cytoplasmic extracts of Xenopus oocytes and eggs.
Autoregulation of tubulin synthesis in hepatocytes and fibroblasts.