Marc Kirschner, PhD

John Franklin Enders University Professor of Systems Biology, Harvard Medical School
In vitro reconstitution of cdc42-mediated actin assembly using purified components.
Authors: Authors: Ho HY, Rohatgi R, Lebensohn AM, Kirschner MW.
Methods Enzymol
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Chemical inhibition of N-WASP by stabilization of a native autoinhibited conformation.
Authors: Authors: Peterson JR, Bickford LC, Morgan D, Kim AS, Ouerfelli O, Kirschner MW, Rosen MK.
Nat Struct Mol Biol
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Oligonucleotide microarray data mining: search for age-dependent gene expression.
Authors: Authors: Kirschner M, Pujol G, Radu A.
Biochem Biophys Res Commun
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A chemical inhibitor of N-WASP reveals a new mechanism for targeting protein interactions.
Authors: Authors: Peterson JR, Lokey RS, Mitchison TJ, Kirschner MW.
Proc Natl Acad Sci U S A
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Easy passage: germline transgenesis in frogs.
Authors: Authors: Kroll KL, Kirschner MW.
Proc Natl Acad Sci U S A
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The checkpoint protein MAD2 and the mitotic regulator CDC20 form a ternary complex with the anaphase-promoting complex to control anaphase initiation.
Authors: Authors: Fang G, Yu H, Kirschner MW.
Genes Dev
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BIME joins the destruction team.
Authors: Authors: Yamashita YM, Peters JM, King RW, Höög C, Kirschner MW, Zachariae W, Shin TH, Galova M, Obermaier B, Nasmyth K.
Trends Cell Biol
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A 20S complex containing CDC27 and CDC16 catalyzes the mitosis-specific conjugation of ubiquitin to cyclin B.
Authors: Authors: King RW, Peters JM, Tugendreich S, Rolfe M, Hieter P, Kirschner MW.
Cell
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The cell cycle then and now.
Authors: Authors: Kirschner M.
Trends Biochem Sci
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Cyclin activation of p34cdc2.
Authors: Authors: Solomon MJ, Glotzer M, Lee TH, Philippe M, Kirschner MW.
Cell
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