Marc Kirschner, PhD
John Franklin Enders University Professor of Systems Biology, Harvard Medical School
Hemichordates and the origin of chordates.
The tumour suppressor RASSF1A regulates mitosis by inhibiting the APC-Cdc20 complex.
Authors: Authors: Song MS, Song SJ, Ayad NG, Chang JS, Lee JH, Hong HK, Lee H, Choi N, Kim J, Kim H, Kim JW, Choi EJ, Kirschner MW, Lim DS.
Nat Cell Biol
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Nat Cell Biol
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A novel set of Wnt-Frizzled fusion proteins identifies receptor components that activate beta -catenin-dependent signaling.
Authors: Authors: Holmen SL, Salic A, Zylstra CR, Kirschner MW, Williams BO.
J Biol Chem
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J Biol Chem
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Information access. Building a "GenBank" of the published literature.
Authors: Authors: Roberts RJ, Varmus HE, Ashburner M, Brown PO, Eisen MB, Khosla C, Kirschner M, Nusse R, Scott M, Wold B.
Science
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Science
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The interaction between N-WASP and the Arp2/3 complex links Cdc42-dependent signals to actin assembly.
Authors: Authors: Rohatgi R, Ma L, Miki H, Lopez M, Kirchhausen T, Takenawa T, Kirschner MW.
Cell
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Cell
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Identification of a cullin homology region in a subunit of the anaphase-promoting complex.
Authors: Authors: Yu H, Peters JM, King RW, Page AM, Hieter P, Kirschner MW.
Science
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Science
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Identification of BIME as a subunit of the anaphase-promoting complex.
The role of microtubule dynamics in growth cone motility and axonal growth.
Microtubule behavior in the growth cones of living neurons during axon elongation.
Dominoes and clocks: the union of two views of the cell cycle.