Marc Kirschner, PhD
John Franklin Enders University Professor of Systems Biology, Harvard Medical School
Dynamic instability of microtubule growth.
Regulation of microtubule and actin filament assembly--disassembly by associated small and large molecules.
A cytoplasmic clock with the same period as the division cycle in Xenopus eggs.
Authors: Authors: Hara K, Tydeman P, Kirschner M.
Proc Natl Acad Sci U S A
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Proc Natl Acad Sci U S A
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Evidence for a functional role of RNA in centrioles.
Mouse embryonic stem cells can differentiate via multiple paths to the same state.
Authors: Authors: Briggs JA, Li VC, Lee S, Woolf CJ, Klein A, Kirschner MW.
Elife
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Elife
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Droplet barcoding for single-cell transcriptomics applied to embryonic stem cells.
Authors: Authors: Klein AM, Mazutis L, Akartuna I, Tallapragada N, Veres A, Li V, Peshkin L, Weitz DA, Kirschner MW.
Cell
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Cell
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Cell-cycle-regulated activation of Akt kinase by phosphorylation at its carboxyl terminus.
Authors: Authors: Liu P, Begley M, Michowski W, Inuzuka H, Ginzberg M, Gao D, Tsou P, Gan W, Papa A, Kim BM, Wan L, Singh A, Zhai B, Yuan M, Wang Z, Gygi SP, Lee TH, Lu KP, Toker A, Pandolfi PP, Asara JM, Kirschner MW, Sicinski P, Cantley L, Wei W.
Nature
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Nature
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Synthesis and evaluation of hybrid drugs for a potential HIV/AIDS-malaria combination therapy.
Authors: Authors: Aminake MN, Mahajan A, Kumar V, Hans R, Wiesner L, Taylor D, de Kock C, Grobler A, Smith PJ, Kirschner M, Rethwilm A, Pradel G, Chibale K.
Bioorg Med Chem
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Bioorg Med Chem
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A general lack of compensation for gene dosage in yeast.
cDNA sequences for transcription factors and signaling proteins of the hemichordate Saccoglossus kowalevskii: efficacy of the expressed sequence tag (EST) approach for evolutionary and developmental studies of a new organism.
Authors: Authors: Freeman RM, Wu M, Cordonnier-Pratt MM, Pratt LH, Gruber CE, Smith M, Lander ES, Stange-Thomann N, Lowe CJ, Gerhart J, Kirschner M.
Biol Bull
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Biol Bull
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