Marc Kirschner, PhD

John Franklin Enders University Professor of Systems Biology, Harvard Medical School
Properties of the kinetochore in vitro. I. Microtubule nucleation and tubulin binding.
Authors: Authors: Mitchison TJ, Kirschner MW.
J Cell Biol
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The redistribution of a conserved nuclear envelope protein during the cell cycle suggests a pathway for chromosome condensation.
Authors: Authors: McKeon FD, Tuffanelli DL, Kobayashi S, Kirschner MW.
Cell
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Nucleotide and corresponding amino acid sequences encoded by alpha and beta tubulin mRNAs.
Authors: Authors: Valenzuela P, Quiroga M, Zaldivar J, Rutter WJ, Kirschner MW, Cleveland DW.
Nature
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Aspartate transcarbamoylase (Escherichia coli): preparation of subunits.
Authors: Authors: Yang YR, Kirschner MW, Schachman HK.
Methods Enzymol
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Cell size sensing in animal cells coordinates anabolic growth rates and cell cycle progression to maintain cell size uniformity.
Authors: Authors: Ginzberg MB, Chang N, D'Souza H, Patel N, Kafri R, Kirschner MW.
Elife
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Correction: Dorsoventral Patterning in Hemichordates: Insights into Early Chordate Evolution.
Authors: Authors: Lowe CJ, Terasaki M, Wu M, Freeman RM, Runft L, Kwan K, Haigo S, Aronowicz J, Lander E, Gruber C, Smith M, Kirschner M, Gerhart J.
PLoS Biol
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Deep proteomics of the Xenopus laevis egg using an mRNA-derived reference database.
Authors: Authors: Wühr M, Freeman RM, Presler M, Horb ME, Peshkin L, Gygi S, Kirschner MW.
Curr Biol
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Deubiquitinase FAM/USP9X interacts with the E3 ubiquitin ligase SMURF1 protein and protects it from ligase activity-dependent self-degradation.
Authors: Authors: Xie Y, Avello M, Schirle M, McWhinnie E, Feng Y, Bric-Furlong E, Wilson C, Nathans R, Zhang J, Kirschner MW, Huang SM, Cong F.
J Biol Chem
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Thiostrepton and derivatives exhibit antimalarial and gametocytocidal activity by dually targeting parasite proteasome and apicoplast.
Authors: Authors: Aminake MN, Schoof S, Sologub L, Leubner M, Kirschner M, Arndt HD, Pradel G.
Antimicrob Agents Chemother
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Tankyrase inhibition stabilizes axin and antagonizes Wnt signalling.
Authors: Authors: Huang SM, Mishina YM, Liu S, Cheung A, Stegmeier F, Michaud GA, Charlat O, Wiellette E, Zhang Y, Wiessner S, Hild M, Shi X, Wilson CJ, Mickanin C, Myer V, Fazal A, Tomlinson R, Serluca F, Shao W, Cheng H, Shultz M, Rau C, Schirle M, Schlegl J, Ghidelli S, Fawell S, Lu C, Curtis D, Kirschner MW, Lengauer C, Finan PM, Tallarico JA, Bouwmeester T, Porter JA, Bauer A, Cong F.
Nature
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