Michael Springer, PhD

Associate Professor of Systems Biology, Harvard Medical School
Abundance-based classifier for the prediction of mass spectrometric peptide detectability upon enrichment (PPA).
Authors: Authors: Muntel J, Boswell SA, Tang S, Ahmed S, Wapinski I, Foley G, Steen H, Springer M.
Mol Cell Proteomics
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Stable isotope-free relative and absolute quantitation of protein phosphorylation stoichiometry by MS.
Authors: Authors: Steen H, Jebanathirajah JA, Springer M, Kirschner MW.
Proc Natl Acad Sci U S A
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Assigning function to natural allelic variation via dynamic modeling of gene network induction.
Authors: Authors: Richard M, Chuffart F, Duplus-Bottin H, Pouyet F, Spichty M, Fulcrand E, Entrevan M, Barthelaix A, Springer M, Jost D, Yvert G.
Mol Syst Biol
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A Chromatin-Based Mechanism for Limiting Divergent Noncoding Transcription.
Authors: Authors: Marquardt S, Escalante-Chong R, Pho N, Wang J, Churchman LS, Springer M, Buratowski S.
Cell
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A distal, high-affinity binding site on the cyclin-CDK substrate Pho4 is important for its phosphorylation and regulation.
Authors: Authors: Byrne M, Miller N, Springer M, O'Shea EK.
J Mol Biol
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Polymorphisms in the yeast galactose sensor underlie a natural continuum of nutrient-decision phenotypes.
Authors: Authors: Lee KB, Wang J, Palme J, Escalante-Chong R, Hua B, Springer M.
PLoS Genet
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A chromatin-based mechanism for limiting divergent noncoding transcription.
Authors: Authors: Marquardt S, Escalante-Chong R, Pho N, Wang J, Churchman LS, Springer M, Buratowski S.
Cell
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Partially phosphorylated Pho4 activates transcription of a subset of phosphate-responsive genes.
Authors: Authors: Springer M, Wykoff DD, Miller N, O'Shea EK.
PLoS Biol
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Achieving global perfect homeostasis through transporter regulation.
Authors: Authors: Savir Y, Martynov A, Springer M.
PLoS Comput Biol
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SnapShot-Seq: a method for extracting genome-wide, in vivo mRNA dynamics from a single total RNA sample.
Authors: Authors: Gray JM, Harmin DA, Boswell SA, Cloonan N, Mullen TE, Ling JJ, Miller N, Kuersten S, Ma YC, McCarroll SA, Grimmond SM, Springer M.
PLoS One
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