Michael Springer, PhD
Associate Professor of Systems Biology, Harvard Medical School
Viral discovery and sequence recovery using DNA microarrays.
Authors: Authors: Wang D, Urisman A, Liu YT, Springer M, Ksiazek TG, Erdman DD, Mardis ER, Hickenbotham M, Magrini V, Eldred J, Latreille JP, Wilson RK, Ganem D, DeRisi JL.
PLoS Biol
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PLoS Biol
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Aneuploidy Causes Non-genetic Individuality.
Authors: Authors: Beach RR, Ricci-Tam C, Brennan CM, Moomau CA, Hsu PH, Hua B, Silberman RE, Springer M, Amon A.
Cell
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Cell
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Mutations in LYRM4, encoding iron-sulfur cluster biogenesis factor ISD11, cause deficiency of multiple respiratory chain complexes.
Authors: Authors: Lim SC, Friemel M, Marum JE, Tucker EJ, Bruno DL, Riley LG, Christodoulou J, Kirk EP, Boneh A, DeGennaro CM, Springer M, Mootha VK, Rouault TA, Leimkühler S, Thorburn DR, Compton AG.
Hum Mol Genet
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Hum Mol Genet
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Total RNA-seq to identify pharmacological effects on specific stages of mRNA synthesis.
Authors: Authors: Boswell SA, Snavely A, Landry HM, Churchman LS, Gray JM, Springer M.
Nat Chem Biol
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Nat Chem Biol
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Profiling of ubiquitin-like modifications reveals features of mitotic control.
Authors: Authors: Merbl Y, Refour P, Patel H, Springer M, Kirschner MW.
Cell
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Cell
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Mutation effects predicted from sequence co-variation.
Authors: Authors: Hopf TA, Ingraham JB, Poelwijk FJ, Schärfe CP, Springer M, Sander C, Marks DS.
Nat Biotechnol
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Nat Biotechnol
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Expression divergence measured by transcriptome sequencing of four yeast species.
Authors: Authors: Busby MA, Gray JM, Costa AM, Stewart C, Stromberg MP, Barnett D, Chuang JH, Springer M, Marth GT.
BMC Genomics
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BMC Genomics
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Probabilistic adaptation in changing microbial environments.
A general lack of compensation for gene dosage in yeast.
A competitive trade-off limits the selective advantage of increased antibiotic production.