Nathanael Gray, PhD

Nancy Lurie Marks Professor of Biological Chemistry and Molecular Pharmacology in the Field of Medical Oncology, Dana-Farber Cancer Institute
First SAR Study for Overriding NRAS Mutant Driven Acute Myeloid Leukemia.
Authors: Authors: Cho H, Shin I, Ju E, Choi S, Hur W, Kim H, Hong E, Kim ND, Choi HG, Gray NS, Sim T.
J Med Chem
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The dTAG system for immediate and target-specific protein degradation.
Authors: Authors: Nabet B, Roberts JM, Buckley DL, Paulk J, Dastjerdi S, Yang A, Leggett AL, Erb MA, Lawlor MA, Souza A, Scott TG, Vittori S, Perry JA, Qi J, Winter GE, Wong KK, Gray NS, Bradner JE.
Nat Chem Biol
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YY1 Is a Structural Regulator of Enhancer-Promoter Loops.
Authors: Authors: Weintraub AS, Li CH, Zamudio AV, Sigova AA, Hannett NM, Day DS, Abraham BJ, Cohen MA, Nabet B, Buckley DL, Guo YE, Hnisz D, Jaenisch R, Bradner JE, Gray NS, Young RA.
Cell
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Progress towards a public chemogenomic set for protein kinases and a call for contributions.
Authors: Authors: Drewry DH, Wells CI, Andrews DM, Angell R, Al-Ali H, Axtman AD, Capuzzi SJ, Elkins JM, Ettmayer P, Frederiksen M, Gileadi O, Gray N, Hooper A, Knapp S, Laufer S, Luecking U, Michaelides M, Müller S, Muratov E, Denny RA, Saikatendu KS, Treiber DK, Zuercher WJ, Willson TM.
PLoS One
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Structure-Activity Relationship Study of QL47: A Broad-Spectrum Antiviral Agent.
Authors: Authors: Liang Y, de Wispelaere M, Carocci M, Liu Q, Wang J, Yang PL, Gray NS.
ACS Med Chem Lett
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Mitotic MELK-eIF4B signaling controls protein synthesis and tumor cell survival.
Authors: Authors: Wang Y, Begley M, Li Q, Huang HT, Lako A, Eck MJ, Gray NS, Mitchison TJ, Cantley LC, Zhao JJ.
Proc Natl Acad Sci U S A
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Targeting Myddosome Assembly in Waldenstrom Macroglobulinaemia.
Authors: Authors: Liu X, Hunter ZR, Xu L, Chen J, Chen JG, Tsakmaklis N, Patterson CJ, Castillo JJ, Buhrlage S, Gray N, Treon SP, Yang G.
Br J Haematol
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CDK7-dependent transcriptional addiction in triple-negative breast cancer.
Authors: Authors: Wang Y, Zhang T, Kwiatkowski N, Abraham BJ, Lee TI, Xie S, Yuzugullu H, Von T, Li H, Lin Z, Stover DG, Lim E, Wang ZC, Iglehart JD, Young RA, Gray NS, Zhao JJ.
Cell
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EPHA2 is a mediator of vemurafenib resistance and a novel therapeutic target in melanoma.
Authors: Authors: Miao B, Ji Z, Tan L, Taylor M, Zhang J, Choi HG, Frederick DT, Kumar R, Wargo JA, Flaherty KT, Gray NS, Tsao H.
Cancer Discov
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Tivantinib (ARQ 197) efficacy is independent of MET inhibition in non-small-cell lung cancer cell lines.
Authors: Authors: Calles A, Kwiatkowski N, Cammarata BK, Ercan D, Gray NS, Jänne PA.
Mol Oncol
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