Peter Sorger, PhD

Otto Krayer Professor of Systems Pharmacology, Harvard Medical School
Measuring Cancer Drug Sensitivity and Resistance in Cultured Cells.
Authors: Authors: Niepel M, Hafner M, Chung M, Sorger PK.
Curr Protoc Chem Biol
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Fractional killing arises from cell-to-cell variability in overcoming a caspase activity threshold.
Authors: Authors: Roux J, Hafner M, Bandara S, Sims JJ, Hudson H, Chai D, Sorger PK.
Mol Syst Biol
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Modulating cell-to-cell variability and sensitivity to death ligands by co-drugging.
Authors: Authors: Flusberg DA, Sorger PK.
Phys Biol
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Kinome-wide selectivity profiling of ATP-competitive mammalian target of rapamycin (mTOR) inhibitors and characterization of their binding kinetics.
Authors: Authors: Liu Q, Kirubakaran S, Hur W, Niepel M, Westover K, Thoreen CC, Wang J, Ni J, Patricelli MP, Vogel K, Riddle S, Waller DL, Traynor R, Sanda T, Zhao Z, Kang SA, Zhao J, Look AT, Sorger PK, Sabatini DM, Gray NS.
J Biol Chem
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Elevated GM-CSF and IL-1beta levels compromise the ability of p38 MAPK inhibitors to modulate TNFalpha levels in the human monocytic/macrophage U937 cell line.
Authors: Authors: Espelin CW, Goldsipe A, Sorger PK, Lauffenburger DA, de Graaf D, Hendriks BS.
Mol Biosyst
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Report on EU-USA workshop: how systems biology can advance cancer research (27 October 2008).
Authors: Authors: Aebersold R, Auffray C, Baney E, Barillot E, Brazma A, Brett C, Brunak S, Butte A, Califano A, Celis J, Cufer T, Ferrell J, Galas D, Gallahan D, Gatenby R, Goldbeter A, Hace N, Henney A, Hood L, Iyengar R, Jackson V, Kallioniemi O, Klingmüller U, Kolar P, Kolch W, Kyriakopoulou C, Laplace F, Lehrach H, Marcus F, Matrisian L, Nolan G, Pelkmans L, Potti A, Sander C, Seljak M, Singer D, Sorger P, Stunnenberg H, Superti-Furga G, Uhlen M, Vidal M, Weinstein J, Wigle D, Williams M, Wolkenhauer O, Zhivotovsky B, Zinovyev A, Zupan B.
Mol Oncol
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Comparative autoregressive moving average analysis of kinetochore microtubule dynamics in yeast.
Authors: Authors: Jaqaman K, Dorn JF, Jelson GS, Tytell JD, Sorger PK, Danuser G.
Biophys J
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Molecular organization of the Ndc80 complex, an essential kinetochore component.
Authors: Authors: Wei RR, Sorger PK, Harrison SC.
Proc Natl Acad Sci U S A
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Electronic detection of DNA by its intrinsic molecular charge.
Authors: Authors: Fritz J, Cooper EB, Gaudet S, Sorger PK, Manalis SR.
Proc Natl Acad Sci U S A
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In vitro assays for studying Saccharomyces cerevisiae kinetochore activity.
Authors: Authors: Severin F, Kaplan K, Sorger P, Hyman T.
Methods Cell Biol
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