Peter Sorger, PhD

Otto Krayer Professor of Systems Pharmacology, Harvard Medical School
Dissecting variability in responses to cancer chemotherapy through systems pharmacology.
Authors: Authors: Yang R, Niepel M, Mitchison TK, Sorger PK.
Clin Pharmacol Ther
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Modeling a snap-action, variable-delay switch controlling extrinsic cell death.
Authors: Authors: Albeck JG, Burke JM, Spencer SL, Lauffenburger DA, Sorger PK.
PLoS Biol
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Systems biology and combination therapy in the quest for clinical efficacy.
Authors: Authors: Fitzgerald JB, Schoeberl B, Nielsen UB, Sorger PK.
Nat Chem Biol
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A dual role for Bub1 in the spindle checkpoint and chromosome congression.
Authors: Authors: Meraldi P, Sorger PK.
EMBO J
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Automatic fluorescent tag detection in 3D with super-resolution: application to the analysis of chromosome movement.
Authors: Authors: Thomann D, Rines DR, Sorger PK, Danuser G.
J Microsc
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Chromosome movement: kinetochores motor along.
Authors: Authors: Grancell A, Sorger PK.
Curr Biol
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Heat shock factor is regulated differently in yeast and HeLa cells.
Authors: Authors: Sorger PK, Lewis MJ, Pelham HR.
Nature
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Author Correction: Immunogenomic profiling determines responses to combined PARP and PD-1 inhibition in ovarian cancer.
Authors: Authors: Färkkilä A, Gulhan DC, Casado J, Jacobson CA, Nguyen H, Kochupurakkal B, Maliga Z, Yapp C, Chen YA, Schapiro D, Zhou Y, Graham JR, Dezube BJ, Munster P, Santagata S, Garcia E, Rodig S, Lako A, Chowdhury D, Shapiro GI, Matulonis UA, Park PJ, Hautaniemi S, Sorger PK, Swisher EM, D'Andrea AD, Konstantinopoulos PA.
Nat Commun
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A curative combination cancer therapy achieves high fractional cell killing through low cross-resistance and drug additivity.
Authors: Authors: Palmer AC, Chidley C, Sorger PK.
Elife
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Highly multiplexed immunofluorescence imaging of human tissues and tumors using t-CyCIF and conventional optical microscopes.
Authors: Authors: Lin JR, Izar B, Wang S, Yapp C, Mei S, Shah PM, Santagata S, Sorger PK.
Elife
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