Peter Sorger, PhD

Otto Krayer Professor of Systems Pharmacology, Harvard Medical School
BID preferentially activates BAK while BIM preferentially activates BAX, affecting chemotherapy response.
Authors: Authors: Sarosiek KA, Chi X, Bachman JA, Sims JJ, Montero J, Patel L, Flanagan A, Andrews DW, Sorger P, Letai A.
Mol Cell
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Sequential application of anticancer drugs enhances cell death by rewiring apoptotic signaling networks.
Authors: Authors: Lee MJ, Ye AS, Gardino AK, Heijink AM, Sorger PK, MacBeath G, Yaffe MB.
Cell
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Measuring and modeling apoptosis in single cells.
Authors: Authors: Spencer SL, Sorger PK.
Cell
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The logic of EGFR/ErbB signaling: theoretical properties and analysis of high-throughput data.
Authors: Authors: Samaga R, Saez-Rodriguez J, Alexopoulos LG, Sorger PK, Klamt S.
PLoS Comput Biol
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Anaphase initiation is regulated by antagonistic ubiquitination and deubiquitination activities.
Authors: Authors: Stegmeier F, Rape M, Draviam VM, Nalepa G, Sowa ME, Ang XL, McDonald ER, Li MZ, Hannon GJ, Sorger PK, Kirschner MW, Harper JW, Elledge SJ.
Nature
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Yeast kinetochore microtubule dynamics analyzed by high-resolution three-dimensional microscopy.
Authors: Authors: Dorn JF, Jaqaman K, Rines DR, Jelson GS, Sorger PK, Danuser G.
Biophys J
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Automatic fluorescent tag localization II: Improvement in super-resolution by relative tracking.
Authors: Authors: Thomann D, Dorn J, Sorger PK, Danuser G.
J Microsc
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Mitotic checkpoints, genetic instability, and cancer.
Authors: Authors: Dobles M, Sorger PK.
Cold Spring Harb Symp Quant Biol
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S-phase feedback control in budding yeast independent of tyrosine phosphorylation of p34cdc28.
Authors: Authors: Sorger PK, Murray AW.
Nature
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Biophysical prediction of protein-peptide interactions and signaling networks using machine learning.
Authors: Authors: Cunningham JM, Koytiger G, Sorger PK, AlQuraishi M.
Nat Methods
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