Peter Sorger, PhD

Otto Krayer Professor of Systems Pharmacology, Harvard Medical School
Highly multiplexed immunofluorescence imaging of human tissues and tumors using t-CyCIF and conventional optical microscopes.
Authors: Authors: Lin JR, Izar B, Wang S, Yapp C, Mei S, Shah PM, Santagata S, Sorger PK.
Elife
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Alternative drug sensitivity metrics improve preclinical cancer pharmacogenomics.
Authors: Authors: Hafner M, Niepel M, Sorger PK.
Nat Biotechnol
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Systematic analysis of BRAF(V600E) melanomas reveals a role for JNK/c-Jun pathway in adaptive resistance to drug-induced apoptosis.
Authors: Authors: Fallahi-Sichani M, Moerke NJ, Niepel M, Zhang T, Gray NS, Sorger PK.
Mol Syst Biol
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Mass spectrometry based method to increase throughput for kinome analyses using ATP probes.
Authors: Authors: McAllister FE, Niepel M, Haas W, Huttlin E, Sorger PK, Gygi SP.
Anal Chem
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p31(comet) acts to ensure timely spindle checkpoint silencing subsequent to kinetochore attachment.
Authors: Authors: Hagan RS, Manak MS, Buch HK, Meier MG, Meraldi P, Shah JV, Sorger PK.
Mol Biol Cell
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Networks inferred from biochemical data reveal profound differences in toll-like receptor and inflammatory signaling between normal and transformed hepatocytes.
Authors: Authors: Alexopoulos LG, Saez-Rodriguez J, Cosgrove BD, Lauffenburger DA, Sorger PK.
Mol Cell Proteomics
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Microfluidics closes in on point-of-care assays.
Authors: Authors: Sorger PK.
Nat Biotechnol
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The human kinetochore proteins Nnf1R and Mcm21R are required for accurate chromosome segregation.
Authors: Authors: McAinsh AD, Meraldi P, Draviam VM, Toso A, Sorger PK.
EMBO J
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Cell biology: the more MAD, the merrier.
Authors: Authors: Hagan RS, Sorger PK.
Nature
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Bayesian network approach to cell signaling pathway modeling.
Authors: Authors: Sachs K, Gifford D, Jaakkola T, Sorger P, Lauffenburger DA.
Sci STKE
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