Peter Sorger, PhD
Otto Krayer Professor of Systems Pharmacology, Harvard Medical School
Multiplexed immunofluorescence reveals potential PD-1/PD-L1 pathway vulnerabilities in craniopharyngioma.
Authors: Authors: Coy S, Rashid R, Lin JR, Du Z, Donson AM, Hankinson TC, Foreman NK, Manley PE, Kieran MW, Reardon DA, Sorger PK, Santagata S.
Neuro Oncol
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Neuro Oncol
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Fundamental trade-offs between information flow in single cells and cellular populations.
Authors: Authors: Suderman R, Bachman JA, Smith A, Sorger PK, Deeds EJ.
Proc Natl Acad Sci U S A
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Proc Natl Acad Sci U S A
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A noncanonical Frizzled2 pathway regulates epithelial-mesenchymal transition and metastasis.
Authors: Authors: Gujral TS, Chan M, Peshkin L, Sorger PK, Kirschner MW, MacBeath G.
Cell
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Cell
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Spindle checkpoint deficiency is tolerated by murine epidermal cells but not hair follicle stem cells.
Authors: Authors: Foijer F, DiTommaso T, Donati G, Hautaviita K, Xie SZ, Heath E, Smyth I, Watt FM, Sorger PK, Bradley A.
Proc Natl Acad Sci U S A
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Proc Natl Acad Sci U S A
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Rapid phospho-turnover by receptor tyrosine kinases impacts downstream signaling and drug binding.
Authors: Authors: Kleiman LB, Maiwald T, Conzelmann H, Lauffenburger DA, Sorger PK.
Mol Cell
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Mol Cell
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Systematic calibration of a cell signaling network model.
Authors: Authors: Kim KA, Spencer SL, Albeck JG, Burke JM, Sorger PK, Gaudet S, Kim DH.
BMC Bioinformatics
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BMC Bioinformatics
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Structural and functional dissection of Mif2p, a conserved DNA-binding kinetochore protein.
Authors: Authors: Cohen RL, Espelin CW, De Wulf P, Sorger PK, Harrison SC, Simons KT.
Mol Biol Cell
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Mol Biol Cell
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Cells on chips.
A reductionist's systems biology: opinion.
Quantitative microscopy of green fluorescent protein-labeled yeast.