Peter Sorger, PhD

Otto Krayer Professor of Systems Pharmacology, Harvard Medical School
Development of a Selective CDK7 Covalent Inhibitor Reveals Predominant Cell-Cycle Phenotype.
Authors: Authors: Olson CM, Liang Y, Leggett A, Park WD, Li L, Mills CE, Elsarrag SZ, Ficarro SB, Zhang T, Düster R, Geyer M, Sim T, Marto JA, Sorger PK, Westover KD, Lin CY, Kwiatkowski N, Gray NS.
Cell Chem Biol
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Quantification of sensitivity and resistance of breast cancer cell lines to anti-cancer drugs using GR metrics.
Authors: Authors: Hafner M, Heiser LM, Williams EH, Niepel M, Wang NJ, Korkola JE, Gray JW, Sorger PK.
Sci Data
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Reproducibility will only come with data liberation.
Authors: Authors: AlQuraishi M, Sorger PK.
Sci Transl Med
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Profiles of Basal and stimulated receptor signaling networks predict drug response in breast cancer lines.
Authors: Authors: Niepel M, Hafner M, Pace EA, Chung M, Chai DH, Zhou L, Schoeberl B, Sorger PK.
Sci Signal
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Creating and analyzing pathway and protein interaction compendia for modelling signal transduction networks.
Authors: Authors: Kirouac DC, Saez-Rodriguez J, Swantek J, Burke JM, Lauffenburger DA, Sorger PK.
BMC Syst Biol
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Snapshots of protein dynamics and post-translational modifications in one experiment--beta-catenin and its functions.
Authors: Authors: Luckert K, Götschel F, Sorger PK, Hecht A, Joos TO, Pötz O.
Mol Cell Proteomics
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Non-genetic origins of cell-to-cell variability in TRAIL-induced apoptosis.
Authors: Authors: Spencer SL, Gaudet S, Albeck JG, Burke JM, Sorger PK.
Nature
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A functional genomic screen identifies a role for TAO1 kinase in spindle-checkpoint signalling.
Authors: Authors: Draviam VM, Stegmeier F, Nalepa G, Sowa ME, Chen J, Liang A, Hannon GJ, Sorger PK, Harper JW, Elledge SJ.
Nat Cell Biol
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Generating chromosome instability through the simultaneous deletion of Mad2 and p53.
Authors: Authors: Burds AA, Lutum AS, Sorger PK.
Proc Natl Acad Sci U S A
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Profiling receptor tyrosine kinase activation by using Ab microarrays.
Authors: Authors: Nielsen UB, Cardone MH, Sinskey AJ, MacBeath G, Sorger PK.
Proc Natl Acad Sci U S A
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