Peter Sorger, PhD

Otto Krayer Professor of Systems Pharmacology, Harvard Medical School
A functional genomic screen identifies a role for TAO1 kinase in spindle-checkpoint signalling.
Authors: Authors: Draviam VM, Stegmeier F, Nalepa G, Sowa ME, Chen J, Liang A, Hannon GJ, Sorger PK, Harper JW, Elledge SJ.
Nat Cell Biol
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Generating chromosome instability through the simultaneous deletion of Mad2 and p53.
Authors: Authors: Burds AA, Lutum AS, Sorger PK.
Proc Natl Acad Sci U S A
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Profiling receptor tyrosine kinase activation by using Ab microarrays.
Authors: Authors: Nielsen UB, Cardone MH, Sinskey AJ, MacBeath G, Sorger PK.
Proc Natl Acad Sci U S A
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Genetic selection of peptide inhibitors of biological pathways.
Authors: Authors: Norman TC, Smith DL, Sorger PK, Drees BL, O'Rourke SM, Hughes TR, Roberts CJ, Friend SH, Fields S, Murray AW.
Science
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Heat shock factor and the heat shock response.
Authors: Authors: Sorger PK.
Cell
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Fibroblast-tumor cell signaling limits HER2 kinase therapy response via activation of MTOR and antiapoptotic pathways.
Authors: Authors: Zervantonakis IK, Poskus MD, Scott AL, Selfors LM, Lin JR, Dillon DA, Pathania S, Sorger PK, Mills GB, Brugge JS.
Proc Natl Acad Sci U S A
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Inhibition of Haspin Kinase Promotes Cell-Intrinsic and Extrinsic Antitumor Activity.
Authors: Authors: Melms JC, Vallabhaneni S, Mills CE, Yapp C, Chen JY, Morelli E, Waszyk P, Kumar S, Deming D, Moret N, Rodriguez S, Subramanian K, Rogava M, Cartwright ANR, Luoma A, Mei S, Brinker TJ, Miller DM, Spektor A, Schadendorf D, Riggi N, Wucherpfennig KW, Sorger PK, Izar B.
Cancer Res
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A multitargeted probe-based strategy to identify signaling vulnerabilities in cancers.
Authors: Authors: Rao S, Du G, Hafner M, Subramanian K, Sorger PK, Gray NS.
J Biol Chem
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Common and cell-type specific responses to anti-cancer drugs revealed by high throughput transcript profiling.
Authors: Authors: Niepel M, Hafner M, Duan Q, Wang Z, Paull EO, Chung M, Lu X, Stuart JM, Golub TR, Subramanian A, Ma'ayan A, Sorger PK.
Nat Commun
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Growth rate inhibition metrics correct for confounders in measuring sensitivity to cancer drugs.
Authors: Authors: Hafner M, Niepel M, Chung M, Sorger PK.
Nat Methods
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