Peter Sorger, PhD

Otto Krayer Professor of Systems Pharmacology, Harvard Medical School
A multiscale statistical mechanical framework integrates biophysical and genomic data to assemble cancer networks.
Authors: Authors: AlQuraishi M, Koytiger G, Jenney A, MacBeath G, Sorger PK.
Nat Genet
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Phosphotyrosine signaling proteins that drive oncogenesis tend to be highly interconnected.
Authors: Authors: Koytiger G, Kaushansky A, Gordus A, Rush J, Sorger PK, MacBeath G.
Mol Cell Proteomics
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Live cell imaging of yeast.
Authors: Authors: Rines DR, Thomann D, Dorn JF, Goodwin P, Sorger PK.
Cold Spring Harb Protoc
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Impaired SHP2-mediated extracellular signal-regulated kinase activation contributes to gefitinib sensitivity of lung cancer cells with epidermal growth factor receptor-activating mutations.
Authors: Authors: Lazzara MJ, Lane K, Chan R, Jasper PJ, Yaffe MB, Sorger PK, Jacks T, Neel BG, Lauffenburger DA.
Cancer Res
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Studying chromosome instability in the mouse.
Authors: Authors: Foijer F, Draviam VM, Sorger PK.
Biochim Biophys Acta
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Misorientation and reduced stretching of aligned sister kinetochores promote chromosome missegregation in EB1- or APC-depleted cells.
Authors: Authors: Draviam VM, Shapiro I, Aldridge B, Sorger PK.
EMBO J
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The yeast DASH complex forms closed rings on microtubules.
Authors: Authors: Miranda JJ, De Wulf P, Sorger PK, Harrison SC.
Nat Struct Mol Biol
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Tracing the pathway of spindle assembly checkpoint signaling.
Authors: Authors: Gillett ES, Sorger PK.
Dev Cell
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Coupling cell division and cell death to microtubule dynamics.
Authors: Authors: Sorger PK, Dobles M, Tournebize R, Hyman AA.
Curr Opin Cell Biol
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Structure and assembly of turnip crinkle virus. II. Mechanism of reassembly in vitro.
Authors: Authors: Sorger PK, Stockley PG, Harrison SC.
J Mol Biol
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