Peter Sorger, PhD

Otto Krayer Professor of Systems Pharmacology, Harvard Medical School
Decision-tree based model analysis for efficient identification of parameter relations leading to different signaling states.
Authors: Authors: Koch Y, Wolf T, Sorger PK, Eils R, Brors B.
PLoS One
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Real-time imaging of the dynamics of death receptors and therapeutics that overcome TRAIL resistance in tumors.
Authors: Authors: Bagci-Onder T, Agarwal A, Flusberg D, Wanningen S, Sorger P, Shah K.
Oncogene
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Molecular structures and interactions in the yeast kinetochore.
Authors: Authors: Cho US, Corbett KD, Al-Bassam J, Bellizzi JJ, De Wulf P, Espelin CW, Miranda JJ, Simons K, Wei RR, Sorger PK, Harrison SC.
Cold Spring Harb Symp Quant Biol
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Non-genetic cell-to-cell variability and the consequences for pharmacology.
Authors: Authors: Niepel M, Spencer SL, Sorger PK.
Curr Opin Chem Biol
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Phenotypic clustering of yeast mutants based on kinetochore microtubule dynamics.
Authors: Authors: Jaqaman K, Dorn JF, Marco E, Sorger PK, Danuser G.
Bioinformatics
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A systems model of signaling identifies a molecular basis set for cytokine-induced apoptosis.
Authors: Authors: Janes KA, Albeck JG, Gaudet S, Sorger PK, Lauffenburger DA, Yaffe MB.
Science
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Binding of the essential Saccharomyces cerevisiae kinetochore protein Ndc10p to CDEII.
Authors: Authors: Espelin CW, Simons KT, Harrison SC, Sorger PK.
Mol Biol Cell
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Chromosome missegregation and apoptosis in mice lacking the mitotic checkpoint protein Mad2.
Authors: Authors: Dobles M, Liberal V, Scott ML, Benezra R, Sorger PK.
Cell
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Identification of essential components of the S. cerevisiae kinetochore.
Authors: Authors: Doheny KF, Sorger PK, Hyman AA, Tugendreich S, Spencer F, Hieter P.
Cell
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Receptor-based mechanism of relative sensing and cell memory in mammalian signaling networks.
Authors: Authors: Lyashenko E, Niepel M, Dixit PD, Lim SK, Sorger PK, Vitkup D.
Elife
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