Peter Sorger, PhD

Otto Krayer Professor of Systems Pharmacology, Harvard Medical School
Development of CDK2 and CDK5 Dual Degrader TMX-2172.
Authors: Authors: Teng M, Jiang J, He Z, Kwiatkowski NP, Donovan KA, Mills CE, Victor C, Hatcher JM, Fischer ES, Sorger PK, Zhang T, Gray NS.
Angew Chem Int Ed Engl
View full abstract on Pubmed
Development and Characterization of a Wee1 Kinase Degrader.
Authors: Authors: Li Z, Pinch BJ, Olson CM, Donovan KA, Nowak RP, Mills CE, Scott DA, Doctor ZM, Eleuteri NA, Chung M, Sorger PK, Fischer ES, Gray NS.
Cell Chem Biol
View full abstract on Pubmed
Highly multiplexed immunofluorescence imaging of human tissues and tumors using t-CyCIF and conventional optical microscopes.
Authors: Authors: Lin JR, Izar B, Wang S, Yapp C, Mei S, Shah PM, Santagata S, Sorger PK.
Elife
View full abstract on Pubmed
Alternative drug sensitivity metrics improve preclinical cancer pharmacogenomics.
Authors: Authors: Hafner M, Niepel M, Sorger PK.
Nat Biotechnol
View full abstract on Pubmed
Systematic analysis of BRAF(V600E) melanomas reveals a role for JNK/c-Jun pathway in adaptive resistance to drug-induced apoptosis.
Authors: Authors: Fallahi-Sichani M, Moerke NJ, Niepel M, Zhang T, Gray NS, Sorger PK.
Mol Syst Biol
View full abstract on Pubmed
Mass spectrometry based method to increase throughput for kinome analyses using ATP probes.
Authors: Authors: McAllister FE, Niepel M, Haas W, Huttlin E, Sorger PK, Gygi SP.
Anal Chem
View full abstract on Pubmed
p31(comet) acts to ensure timely spindle checkpoint silencing subsequent to kinetochore attachment.
Authors: Authors: Hagan RS, Manak MS, Buch HK, Meier MG, Meraldi P, Shah JV, Sorger PK.
Mol Biol Cell
View full abstract on Pubmed
Networks inferred from biochemical data reveal profound differences in toll-like receptor and inflammatory signaling between normal and transformed hepatocytes.
Authors: Authors: Alexopoulos LG, Saez-Rodriguez J, Cosgrove BD, Lauffenburger DA, Sorger PK.
Mol Cell Proteomics
View full abstract on Pubmed
Microfluidics closes in on point-of-care assays.
Authors: Authors: Sorger PK.
Nat Biotechnol
View full abstract on Pubmed
The human kinetochore proteins Nnf1R and Mcm21R are required for accurate chromosome segregation.
Authors: Authors: McAinsh AD, Meraldi P, Draviam VM, Toso A, Sorger PK.
EMBO J
View full abstract on Pubmed