Peter Sorger, PhD

Otto Krayer Professor of Systems Pharmacology, Harvard Medical School
Discovery of Covalent CDK14 Inhibitors with Pan-TAIRE Family Specificity.
Authors: Authors: Ferguson FM, Doctor ZM, Ficarro SB, Browne CM, Marto JA, Johnson JL, Yaron TM, Cantley LC, Kim ND, Sim T, Berberich MJ, Kalocsay M, Sorger PK, Gray NS.
Cell Chem Biol
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From word models to executable models of signaling networks using automated assembly.
Authors: Authors: Gyori BM, Bachman JA, Subramanian K, Muhlich JL, Galescu L, Sorger PK.
Mol Syst Biol
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Conservation of protein abundance patterns reveals the regulatory architecture of the EGFR-MAPK pathway.
Authors: Authors: Shi T, Niepel M, McDermott JE, Gao Y, Nicora CD, Chrisler WB, Markillie LM, Petyuk VA, Smith RD, Rodland KD, Sorger PK, Qian WJ, Wiley HS.
Sci Signal
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BID preferentially activates BAK while BIM preferentially activates BAX, affecting chemotherapy response.
Authors: Authors: Sarosiek KA, Chi X, Bachman JA, Sims JJ, Montero J, Patel L, Flanagan A, Andrews DW, Sorger P, Letai A.
Mol Cell
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Sequential application of anticancer drugs enhances cell death by rewiring apoptotic signaling networks.
Authors: Authors: Lee MJ, Ye AS, Gardino AK, Heijink AM, Sorger PK, MacBeath G, Yaffe MB.
Cell
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Measuring and modeling apoptosis in single cells.
Authors: Authors: Spencer SL, Sorger PK.
Cell
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The logic of EGFR/ErbB signaling: theoretical properties and analysis of high-throughput data.
Authors: Authors: Samaga R, Saez-Rodriguez J, Alexopoulos LG, Sorger PK, Klamt S.
PLoS Comput Biol
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Anaphase initiation is regulated by antagonistic ubiquitination and deubiquitination activities.
Authors: Authors: Stegmeier F, Rape M, Draviam VM, Nalepa G, Sowa ME, Ang XL, McDonald ER, Li MZ, Hannon GJ, Sorger PK, Kirschner MW, Harper JW, Elledge SJ.
Nature
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Yeast kinetochore microtubule dynamics analyzed by high-resolution three-dimensional microscopy.
Authors: Authors: Dorn JF, Jaqaman K, Rines DR, Jelson GS, Sorger PK, Danuser G.
Biophys J
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Automatic fluorescent tag localization II: Improvement in super-resolution by relative tracking.
Authors: Authors: Thomann D, Dorn J, Sorger PK, Danuser G.
J Microsc
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