Tim Mitchison

Timothy Mitchison, PhD

Hasib Sabbagh Professor of Systems Biology, Harvard Medical School

Tim Mitchison, PhD, received his BA in Biochemistry from Oxford University, England, in 1980, and his PhD from the University of California, San Francisco (UCSF), in Biochemistry and Biophysics in 1984, where he worked with Professor Marc Kirschner. At this time he discovered the dynamic instability of microtubules. Later he worked at the National Institute for Medical Research in London. In 1987 he returned to San Francisco to become an Assistant Professor at UCSF. In 1997 he moved to the Cell Biology Department at Harvard Medical School where he co-founded the Institute for Chemistry and Cell Biology.

Dr. Mitchison was a founding member of the HMS Department of Systems Biology, which started in 2004. He is currently Deputy Chair of the department, and Co-director of the Systems Biology PhD Program. He was elected a Fellow of the Royal Society in 1997, and member of the American Association of Arts and Sciences in 2008. In 2010 he served as President of the American Society of Cell Biology. And most recently in 2014 he became a member of the National Academy of Sciences.

Cytoskeletal dynamics and nerve growth.
Authors: Authors: Mitchison T, Kirschner M.
Neuron
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Assembly properties of fluorescein-labeled tubulin in vitro before and after fluorescence bleaching.
Authors: Authors: Leslie RJ, Saxton WM, Mitchison TJ, Neighbors B, Salmon ED, McIntosh JR.
J Cell Biol
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Autoregulation and repair in microtubule homeostasis.
Authors: Authors: Gasic I, Mitchison TJ.
Curr Opin Cell Biol
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Cell death response to anti-mitotic drug treatment in cell culture, mouse tumor model and the clinic.
Authors: Authors: Shi J, Mitchison TJ.
Endocr Relat Cancer
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Size Scaling of Microtubule Assemblies in Early Xenopus Embryos.
Authors: Authors: Mitchison TJ, Ishihara K, Nguyen P, Wühr M.
Cold Spring Harb Perspect Biol
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Glycogen-supplemented mitotic cytosol for analyzing Xenopus egg microtubule organization.
Authors: Authors: Groen AC, Ngyuen PA, Field CM, Ishihara K, Mitchison TJ.
Methods Enzymol
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The first World Cell Race.
Authors: Authors: Maiuri P, Terriac E, Paul-Gilloteaux P, Vignaud T, McNally K, Onuffer J, Thorn K, Nguyen PA, Georgoulia N, Soong D, Jayo A, Beil N, Beneke J, Lim JC, Sim CP, Chu YS, Jiménez-Dalmaroni A, Joanny JF, Thiery JP, Erfle H, Parsons M, Mitchison TJ, Lim WA, Lennon-Duménil AM, Piel M, Théry M.
Curr Biol
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Coupled, circumferential motions of the cell wall synthesis machinery and MreB filaments in B. subtilis.
Authors: Authors: Garner EC, Bernard R, Wang W, Zhuang X, Rudner DZ, Mitchison T.
Science
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An intermittent live cell imaging screen for siRNA enhancers and suppressors of a kinesin-5 inhibitor.
Authors: Authors: Tsui M, Xie T, Orth JD, Carpenter AE, Rudnicki S, Kim S, Shamu CE, Mitchison TJ.
PLoS One
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Actin-aggregating cucurbitacins from Physocarpus capitatus.
Authors: Authors: Maloney KN, Fujita M, Eggert US, Schroeder FC, Field CM, Mitchison TJ, Clardy J.
J Nat Prod
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