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Novel biologics for cancer therapy

Methods and applications of semi-permeable capsules with current application to high-throughput single cell multi-omics

Developing novel therapeutic approaches for CNS drug delivery by targeting a newly identified key regulator of the blood brain barrier

Computationally designed therapy targeting lysosomal function and inflammation in neurodegenerative diseases

Restoring cortical function and plasticity for the treatment of Alzheimer’s Disease

Microtubule stabilizing drugs for neurodegenerative disease and spinal cord injury

Developing therapeutics for treating Rett syndrome by correcting neuronal long-gene misregulation – Lead compound optimization and in vivo validation

Building better screens and identifying ligands for human MS4A proteins

Development of small molecule modulators of autophagy and ER stress as novel therapeutics for AD

Developing CRISPR-Cas9 reagents for editing lytic and latent herpes simplex virus genomes

Targeting neuro-immune signaling to treat bacterial infections

Isoguvacine and benzodiazepine derivatives for the treatment of tactile hypersensitivity and anxiety in autism spectrum disorders

Development of an inexpensive at-home influenza kit and detection technology

Development of AAV-mediated mini-gene therapy for Usher syndrome type 1F, a combined deafness and blindness

Development of a new precision therapeutic for an important cancer target

Targeting apoptotic pathways for ALS, Alzheimer’s Disease and Parkinson’s Disease

Next-generation AAV therapies for management of intractable chronic pain

Engineered proteins for treatment of pancreatitis

Development of synthetic analogs of a sleeve gastrectomy-induced metabolite as a novel therapy for type 2 diabetes and obesity

A high-throughput platform for the non-invasive intracellular delivery of molecules for therapeutic applications

Target identification of neuroprotective kinase inhibitors for Alzheimer’s and related dementias

Identifying novel therapeutic targets for treating pain and chronic itch

A novel biologic and therapeutic target for the treatment of diabetes

A natural beta interferon-inducing therapeutic glycolipid from the microbiome that prevents and treats severe viral infection