S. aureus is one of the leading causes of human skin and soft tissue infections, and is also associated with the itchy skin disease atopic dermatitis. In this project, we aim to target one of its secreted proteases, V8, using antibodies and vaccination as a novel approach to treat S. aureus infections.
Funding
Funding Duration
July 1, 2025 - June 30, 2026
Funding level
Pilot
People
Principal Investigator
Isaac Chiu
PhD
Assistant Professor of Immunology, Harvard Medical School
Co-PI
Alexander Horswill
PhD
Professor of Immunology and Microbiology, University of Colorado
Collaborators
Samantha Choi
BS
Research Assistant, Harvard Medical School
Liwen Deng
Research Fellow in Immunology (INT), Harvard Medical School
Xinmin Qian
PhD
Research Fellow in Immunology, Harvard Medical School
Johnny Thorsensten
Graduate Research Assistant, University of Colorado