View as cardsView as table106 Projects

Assessment of targeted protein degradation as a strategy for potent antivirals with high barriers to resistance

Fiscal Year Awarded:

2017

Principal Investigator:

Priscilla Yang

Building better screens and identifying ligands for human MS4A proteins

Fiscal Year Awarded:

2017

Principal Investigator:

Sandeep Datta

Developing a ubiquitin-dependent proteasome activity reporter to screen for activators and inhibitors

Fiscal Year Awarded:

2017

Principal Investigator:

Marc Kirschner

Developing therapeutics for treating Rett syndrome by correcting neuronal long-gene misregulation – Lead compound optimization and in vivo validation

Fiscal Year Awarded:

2017

Principal Investigator:

Michael Greenberg

Microtubule stabilizing drugs for neurodegenerative disease and spinal cord injury

Fiscal Year Awarded:

2017

Principal Investigator:

Timothy Mitchison

Restoring cortical function and plasticity for the treatment of Alzheimer’s Disease

Fiscal Year Awarded:

2017

Principal Investigator:

Bernardo Sabatini