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Structure-based discovery and optimization of novel angiotensin receptor modulators

Fiscal Year Awarded:

2024

Principal Investigator:

Andrew Kruse

Targeting tumor endothelial cells for cancer immunotherapy with cytokines

Fiscal Year Awarded:

2024

Principal Investigator:

Ulrich von Andrian

Using microbiome-derived small molecules to augment cancer immunotherapy

Fiscal Year Awarded:

2024

Principal Investigator:

Marco Jost

A kinase inhibitor for malignant brain tumors

Fiscal Year Awarded:

2023

Principal Investigator:

Timothy Mitchison

Agents modulating B cell activation through the CD81-CD19 co-receptor complex

Fiscal Year Awarded:

2023

Principal Investigator:

Stephen Blacklow

Antibody-based therapeutics against Nipah virus

Fiscal Year Awarded:

2023

Principal Investigator:

Jonathan Abraham

Brain-penetrant kinase inhibitors targeting Alzheimer's and related dementias

Fiscal Year Awarded:

2023

Principal Investigator:

Mark Albers

Developing novel agonists of cytokine receptors by targeting receptor pre-clusters

Fiscal Year Awarded:

2023

Principal Investigator:

James Chou

Evaluating antisense oligos for therapeutic impact in liver fibrosis and hepatocellular carcinoma

Fiscal Year Awarded:

2023

Principal Investigator:

Karen Adelman

Identification of druggable targets against Vibrio pathogens

Fiscal Year Awarded:

2023

Principal Investigator:

Norbert Perrimon