Q-FASTR Records

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	Fiscal Year Awarded	Principal Investigator
Small molecule drugs for advanced cancer with ecDNA amplicons	2022	Timothy Mitchison
Small molecule modulators of bile acid metabolism to treat NAFLD/NASH	2022	Sloan Devlin
Studies on immunogenic lipids from the gut microbiome	2022	Jon Clardy
A novel biologic and therapeutic target for the treatment of diabetes	2021	Douglas Melton
Application of the SPLANDID antigen presentation technology to HIV-1 vaccine development	2021	James Chou
Development of an inexpensive at-home influenza kit and detection technology	2021	Michael Springer
Evaluating splicing modulators for therapeutic impact in cohesin-mutant AML and MDS cells	2021	Karen Adelman
Identifying novel therapeutic targets for treating pain and chronic itch	2021	David Ginty
Protein therapeutics for treatment of chronic and inflammatory pain	2021	Pamela Silver
Structure-guided discovery of novel antibiotics inhibiting bacterial cell wall formation	2021	Maofu Liao
Target identification of neuroprotective kinase inhibitors for Alzheimer’s and related dementias	2021	Mark Albers
A high-throughput platform for the non-invasive intracellular delivery of molecules for therapeutic applications	2020	Johan Paulsson
Developing novel therapeutic approaches for CNS drug delivery by targeting a newly identified key regulator of the blood brain barrier	2020	Chenghua Gu
Development of synthetic analogs of a sleeve gastrectomy-induced metabolite as a novel therapy for type 2 diabetes and obesity	2020	Sloan Devlin
Engineered proteins for treatment of pancreatitis	2020	Pamela Silver
Evaluating splicing modulators for therapeutic impact in cohesin-mutant AML and MDS cells	2020	Karen Adelman
Interleukin-17 as a novel erythropoiesis stimulating agent	2020	Allon Klein
Monoclonal antibody-based therapeutics for Argentine hemorrhagic fever	2020	Jonathan Abraham
Multiplex editing the human genome	2020	George Church
Next-generation AAV therapies for management of intractable chronic pain	2020	Michael Greenberg

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