Q-FASTR Records

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	Fiscal Year Awarded	Principal Investigator
Towards the development of improved insect repellents	2026	Josefina del Marmol
V8 protease to treat S. aureus infection and atopic dermatitis	2026	Isaac Chiu
Developing a biomarker of homologous recombination deficiency for enhanced PARP inhibitor efficacy across cancers	2025	Peter Park
Developing a synthetic biology platform for pharmaceutical biomanufacturing	2025	Pamela Silver
Development of allosteric activators for immunotherapy	2025	Stephen Blacklow
Development of small molecule inhibitors of a gut bacterial metabolic toxin	2025	Sloan Devlin
In vivo gene editing to treat inherited Collagen VI-related myopathies	2025	Amy Wagers
In vivo strategy to induce tolerance to therapeutic proteins and autoantigens	2025	Amy Wagers
Investigating the mode of action of a highly selective insecticide and suitability for Anopheles management	2025	Norbert Perrimon
Structure-based discovery of chromatin remodeling inhibitors	2025	Lucas Farnung
Targeting cancers by de-repressing nuclear PDC	2025	David Scadden
Targeting cell surface receptors for ASO delivery to bone marrow leukemia cells	2025	Karen Adelman
Virome screening for next generation nucleic acid delivery vectors to the lung	2025	George Church
Design of novel protease inhibitors to enhance immune checkpoint blockade in cancer therapy	2024	Mark Namchuk
Development of a synthetic promoter pipeline for safe and efficient gene therapy	2024	George Church
Development of novel AAV-mediated in vivo gene editing approaches to treat inherited collagen VI-related myopathies	2024	Amy Wagers
Functional antibody screening with micro-capsules - proof of concept with anti-EGFR	2024	Allon Klein
Gene editing to treat hereditary deafness	2024	David Corey
Identification of small molecule binders of the novel cancer immunotherapy target Bird33	2024	Arlene Sharpe
Multimodal imaging and machine learning for diagnosis and patient stratification with predictive biomarkers	2024	Peter Sorger

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